CONTRACEPTIVES UNMET NEEDS
A triple action contraceptive gel has the potential to take over a significant percentage of the contraceptive market by protecting the end user from both unplanned pregnancy and STDs. The gel, which can be used by both males and females, acts as a spermicidal, bactericidal and libido stimulant. It is fabricated with ingredients already approved by the United States Food and Drug Administration (FDA). Most contraceptive options are only available for women and carry many potential side effects. Contraceptive options available for men are limited to condoms or a vasectomy which is not easily reversible. The contraceptive gel new to the market reduces the risk of unplanned pregnancy and STDs while decreasing the potential side effects of competitive products currently on the market.
BETA THALASSEMIA: NEW GENE EDITING TREATMENT
Our DNA provides the roadmap to life, from the eye color to how well the blood flows through the veins. Changes to the DNA instructions are called mutations and can cause severe life-threatening diseases. β-thalassemia and sickle cell anemia are hereditary hematological diseases that can be caused by hundreds of mutations that reduce the expression of the adult β-globin gene4 or HBB gene1. This produces a reduction in adult hemoglobin and an excess of α-globin content in erythroid cells4. This imbalance of α/β-globin leads to ineffective erythropoiesis, chronic hemolytic anemia, and compensatory hemopoietic expansion6. This disease does not affect everyone on the same way. Non-Transfusion-dependent thalassemia (NTDT) people may require occasional blood transfusions, especially during pregnancy, surgery, and infections, while transfusion-dependent thalassemia (TDT) require blood transfusions or treatments constantly.6 Until 2019, bone marrow transplant was the only curative treatment, when the European Medicine Agency (EMA) approved the first gene therapy treatment6. This literature review will explore the current developments in Gene editing to treat patients with beta Thalassemia.
ALTERNATIVE NON-ANTIBIOTIC TREATMENT FOR NECROTIC ENTERITIS IN THE POULTRY INDUSTRY
The poultry industry has always combated different diseases. Increases in consumer demand for poultry meat have led to an increase of these diseases in the poultry industry, mainly that of diseases such as Necrotic Enteritis (NE). NE is an intestinal disease caused by Clostridium perfringens and negatively impacts the poultry industry worldwide. Antimicrobial Growth Promoters (AGP) have been the primary prevention treatment for NE. However, there is a ban on these products in Europe, and there are also several consumer health concerns. This literature review addresses this topic and alternative non-antibiotic treatments.